UMM, i DO THINK SO! I've been watching them grow so I can get a photo!
I have witnessed this several times and they only swell like this in spring. In 3mths time they will be gone and I won't see them again untill next spring.
With amplexus (in this species) males tuck their fingers under and leave the thumbs out. This area is in exactly the right place for full contact.
I have no experience with most of the frogs you would keep and i'm sure different species would have evolved to suit their own needs but I assure you that I have watched this for just over two years with this being the third spring in a row where I have witnessed this growth and color change. This combined with the fact that they only appear on my males leads me to the conclusion that they must be nuptial pads.
This male is not properly locked in but you can see the fist and where contact will be made when he does go under. Right at the base of that thumb!
Now if you still don't beleive me I can take thumb pics of other males and females just so you know i'm not full of **** but...