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The 'hard evidence' I've heard is that the rat fed snakes in collections just grow larger on rats.
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But growing larger is not always evidence of being healthier. American diets are proof of that.
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Hard to be scientific, but with rats having more to them nutritionally (and mice apparently have a higher fat percentage) it makes sense
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Again, this depends on what age you're looking at. Not all mice have more fat. As in one of my earlier examples, if looking at the same aged mouse and rat - the rat has more fat. So you just can't say anything in generalities with this.
Oh, I long for the day when Herpetology has advanced so far as to gives all the answers we desire!
Interesting discussion. 
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