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If you inbreed with your sister you will see traits good and bad compounded
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Humans have not had natural selection working on them for millions of years to weed out deliterious recessive alleles. Most reptiles in the natural world have. I don't think you can draw comparisons between us and wild animals. We're due for a catastrophic die off. No question. Too much outbreeding? Doubt it. More like too much medicine (creating super bugs) and too much of the weaker getting to breed. Why do you think there are more cases of all the "syndromes" every year. Every single person is kept alive. There is no survival of the fittest in humans. Its survival of EVERYONE. The human race gets significantly weaker every generation. More in some areas than others. But culturally, its impossible for us to evolve. Our sociology won't allow it.
http://www2.uic.edu/~vuletic/top7.html
http://www.aepryus.com/evolizer/BioPaper.html
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