How old are the eldest pups in there? I have seen this before, but usually that was the result of poor breeding and they just don't have it all "upstairs".
Sorry that this is happening....doesn't sound like she will make it (unless you remove her right away, get her on antibiotics, and syringe feed her baby food and warm water). It can be done, but if she isn't worth it to you (as in, she isn't your best producer nor a great pet), then you might want to consider euthying her. I wouldn't put the other female in there right now as the one is very stressed. Maybe try putting some of the pups on her and see how she can handle it.
Let us know what happens!
~Tara
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Balls: Xander, Anya, Jive
Spotteds: Malfoy
Geckos: Spirit & Aimee
Bearded Dragon: Ally
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Non-herps: Tico (Maltese/Poodle), Bo (Maine Coon x), Kahlua (Tortie/Siamese x), Bailey (Maine Coon x), & plenty of hairless and satin rats!
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